Talk:Congenital insensitivity to pain

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Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Congenital insensitivity to pain.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

A summary of this article appears in Pain.

General comments

Just a note-to-self to look this up one day.

Nagasako EM. Oaklander AL. Dworkin RH. Congenital insensitivity to pain: an update. [Review] [43 refs] [Journal Article. Review. Review, Tutorial] Pain. 101(3):213-9, 2003 Feb.

Reading this paper online shows that some of the thoughts about what i've written are slightly out of date, or at least mix'n'matches between indifference and insensitivity. But it's a work in progress. T 05:27, 23 Apr 2004 (UTC)

Um, sorry about the edit - I'm all over the place U R A GR8 M8 15:24, 23 November 2006 (UTC)[reply]

Anesthesia

Would they still anesthetize you if you had to have surgery?--Sagittarian Milky Way 23:58, 18 January 2007 (UTC)[reply]

Just watched an episode of House MD and noticed that the fictional character with CIP didn't need to be anesthetized while she underwent surgery. Since I'm too lazy to actually look this up, I'm gonna go on the ancient wisdom of the FOX network :P 202.76.151.153 12:54, 6 June 2007 (UTC)[reply]

Just watched the same episode, They didnt anesthetize because the nitrous was causing some problem in her system, its my understanding that they usually would to prevent the patient from moving during the procedure--Beanpolekt 19:59, 14 August 2007 (UTC)[reply]

CIP or CIPA

Doesn't CIPA refer to anhidrosis? If so, the opening sentence should be "Congenital insensitivity to pain (CIP)..., no?

Media depictions

The section on media depictions, which deals with fictional presentations, doesn't add much understanding of the condition. Media depictions aren't too reliable, and the truth is usually more interesting. WP:MEDMOS discourages "trivia" sections, and that's what this is. I think it should go. Anyone have a reason to keep it in? --Nbauman (talk) 10:12, 22 November 2012 (UTC)[reply]

The list itself seems useless, but there are ways its contents could be made relevant. If a specific portrayal created controversy or discussion, like some media depictions of albinism have created, that could be relevant(and citeable.) If some specific portrayal was notably accurate or based on a real person, it might be noteworthy. Or if a specific media depiction was very inaccurate, examples from it could be used in the main body of the article to demonstrate myths or misconceptions about the disease by contrasting the depiction with reality(again, citeable.) But, imo, if it's merely supposed to be a list of characters in fiction with this condition, it's something that belongs on TVTropes, not Wikipedia. 97.83.179.39 (talk) 02:48, 4 March 2014 (UTC)[reply]

Mistake in "Types of congenital pain indifference" section

How can you say they will not flinch or withdraw when exposed to pain if they have congenital insensitivity to pain and so can't feel pain at all? It's damaging threats that they will not pull away from, not pain. Blackbombchu (talk) 23:11, 31 July 2013 (UTC)[reply]

Presentation

Is the presentation section worth anything. It just seems like advice to parents with children that have CIP. Also what is the point in the incidences section? This article looks like it needs quite a bit of clean up.76.27.238.105 (talk) 00:22, 13 July 2013 (UTC)[reply]

Inability to Even Get Injured?

Is there such a thing as a tendency to never get injured and therefore do all the damage instead? I imagine that somebody would put his/her/their thumb under a stapler and break that stapler and totally bend the staple that would come out or make a hard heavy object hit the ground when that object would get tossed at him/her/them! Cbsteffen (talk) 04:35, 29 July 2022 (UTC)[reply]

Exaggerated incedence?

The Epidemiology section claims that the incidence 1 in 25,000 births. This seems like a questionably high number - assuming most cases lived relatively normal-length lives, it would imply ~300,000 cases worldwide! The cited source, from the Iranian Journal of Child Neurology, pulls this claim from a case study in the Indian Journal of Anaesthesia, which does not cite a source for its claim. The previous sentence in the introduction of that IJA article does cite a source, however - Peripheral Neuropathy, 3rd Edition by Dyck et al, p. 1065-1093. The cited PN article makes no mention of the 1:25,000 statistic, however the previous article in that publication does reference that exact statistic for an entirely different condition, CMA 1 née "Werdnig-Hoffman disease". (ibid. p. 1053)

I believe that Dave et al of the IJA article mistakenly copied this statistic from the previous article in PN, and the authors of the IJCN article simply took it as a given. A quick Google search led me to this PDF on the University of Hawaii Hilo site that lists the estimated total worldwide cases as 300(!), which feels like a much more reasonable number than 300,000 to me. However, as I am not an expert in any field, let alone neurology, I will refrain from removing or editing the claim. (I think this would at least be worthy of a "dubious" annotation? Unsure.) St (a) Fe.Ph (talk) 04:56, 26 February 2025 (UTC)[reply]

Ah, looked a little more carefully at the UH Hilo PDF: it was actually 300 for CIP with anhidrosis, which is much more specific. (It's past midnight here, I'm tired.) Nonetheless, I don't think I would expect a thousandfold increase in cases without anhidrosis, and the original claim of 1:25,000 still doesn't appear to have much evidence behind it. St (a) Fe.Ph (talk) 05:11, 26 February 2025 (UTC)[reply]

Yes. Ramos1990 (talk) 08:46, 26 February 2025 (UTC)[reply]

Wiki Education assignment: WRIT 1150-19

This article is currently the subject of a Wiki Education Foundation-supported course assignment, between 8 January 2025 and 2 May 2025. Further details are available on the course page. Student editor(s): Cmg365 (article contribs).

— Assignment last updated by Cmg365 (talk) 12:05, 31 March 2025 (UTC)[reply]

Future Editing Plans

I am planning on making some edits to improve this article in the near future. As it is now, this article contains a lot of quality information but does not adhere to all of Wikipedia’s guidelines. First, there are many sentences throughout this article that lack appropriate citations. I am planning on going back through the information that is currently in the article, checking its validity, and adding citations where necessary. Secondly, Wikipedia claims that medicine-related articles should not be “a collection of case studies, and excessive examples should be avoided” (Wikipedia: Manual of Style/Medicine-related articles). Keeping this in mind, I am planning on removing the information related to Jo Cameron in this article, as it does not address congenital insensitivity to pain in a way that is digestible for readers. In the same light, I am planning on adding a paragraph at the beginning of the Signs and Symptoms section that provides an overview of all of the potential symptoms in a broader sense. Through my research and the video on the Wikipedia article, I have gathered a lot of information regarding signs of congenital insensitivity to pain that are not discussed in this article even though they play a crucial role in the diagnosis of the condition. Then I will add a similar paragraph at the beginning of the Causes section, addressing the causes of congenital insensitivity to pain in a more general sense. After adding this paragraph I am planning on writing another paragraph that addresses some of the confusion surrounding the terminology used when talking about congenital insensitivity to pain. Throughout my research, I had some difficulty navigating and determining whether or not congenital insensitivity to pain is actually the name for the diagnosis of this condition or whether that is simply an umbrella term. I think that adding this paragraph will provide a lot of clarity about the actual nature of the condition. I will add this paragraph to a new section I am planning on creating called Classification, which is a section that Wikipedia recommends for medicine-related articles. This section will come after the Lead section but before the Signs and Symptoms section. Finally, I am planning on adjusting the Lead section to reflect these changes I am planning on making. At the moment, the Lead section contains information that is not discussed further in the article, which goes against Wikipedia’s guidelines. For information about the sources I am planning on using please see my annotated bibliography in the bibliography sandbox on my Wikipedia dashboard. Cmg365 (talk) 12:46, 2 April 2025 (UTC)[reply]